Vincent Romanet Selected Research

CHZ868

7/2015	Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.
7/2015	CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.

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Vincent Romanet Research Topics

Disease

14	Neoplasms (Cancer) 04/2024 - 01/2012
4	Splenomegaly 01/2019 - 11/2013
2	Melanoma (Melanoma, Malignant) 01/2024 - 02/2014
2	Breast Neoplasms (Breast Cancer) 01/2023 - 12/2012
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 07/2015 - 02/2012
2	Primary Myelofibrosis (Myelosclerosis) 03/2015 - 11/2013
1	Werner Syndrome (Werner's Syndrome) 04/2024
1	Microsatellite Instability 04/2024
1	Triple Negative Breast Neoplasms 01/2023
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2017
1	Polycythemia (Erythrocytosis) 11/2016
1	Necrosis 02/2014
1	Polycythemia Vera 02/2013
1	Body Weight (Weight, Body) 02/2013
1	Anemia 02/2013
1	Rhabdoid Tumor (Rhabdoid Tumors) 01/2013
1	Wilms Tumor (Wilm's Tumor) 05/2012
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2012

Drug/Important Bio-Agent (IBA)

4	Janus Kinase InhibitorsIBA 01/2019 - 11/2013
3	ruxolitinibIBA 03/2015 - 02/2013
2	Phosphotransferases (Kinase)IBA 01/2023 - 03/2015
2	siremadlinIBA 11/2018 - 01/2017
2	CHZ868IBA 07/2015 - 07/2015
1	RecQ HelicasesIBA 04/2024
1	Biomarkers (Surrogate Marker)IBA 01/2024
1	Inositol (Myoinositol)IBA 01/2024
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2024
1	tyrosine receptor (receptor, tyrosine)IBA 01/2023
1	Protein Tyrosine PhosphatasesIBA 01/2023
1	Proto-Oncogene Proteins c-mdm2IBA 01/2017
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 01/2017
1	Tumor Suppressor Protein p53IBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	IronIBA 11/2016
1	CytokinesIBA 03/2015
1	Caspase 3 (Caspase-3)IBA 02/2014
1	Everolimus FDA Link 02/2014
1	PanobinostatIBA 11/2013
1	Janus KinasesIBA 11/2013
1	Hydroxyurea (Hydrea)FDA LinkGeneric 02/2013
1	Erythropoietin FDA Link 02/2013
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2013
1	Interleukin-8 (Interleukin 8)IBA 12/2012
1	NVP-BKM120IBA 08/2012
1	Insulin-Like PeptidesIBA 05/2012
1	DNA (Deoxyribonucleic Acid)IBA 05/2012
1	NVP-AEW541IBA 05/2012
1	Cytokine Receptors (Cytokine Receptor)IBA 02/2012
1	Janus Kinase 2IBA 02/2012
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2012

Therapy/Procedure

5	Therapeutics 01/2023 - 01/2012
1	Transplantation 11/2013